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State lawmakers and regulatory departments are now being tasked to best enact appropriate laws, rules, and regulations on the use of cannabis for both medicinal and recreational purposes. Considering these issues, evaluation of the exposure from contaminated cannabis needs to be urgently addressed so that new regulations can be properly guided. Mainstream smoke consists of the smoke inhaled from a smoking device directly while sidestream smoke refers to smoke that otherwise escapes the device and is not directly inhaled. Preparation of Calibration Curves Three sets of calibration curves were prepared, each in different matrixes that consisted of smoked plant material solutions in order to account for possible ion suppression from the matrixes. Industrial and other laboratories have attempted to quantify the levels at which pesticide residues transfer into the smoke stream in order to validate what quantities of pesticides may safely be applied to crops, and these values have been used to help moderate the levels of pesticide exposure of the public [ 5 , 11 ]. This material was then separated and sifted over a rough screen to further remove small non-leafy material. Considering these results, high pesticide exposure through cannabis smoking is a significant possibility, which may lead to further health complications in cannabis consumers. All glassware, tubing, and smoking devices were then washed thoroughly with methanol and acetone between experiments. Results The calibration solutions of chemical residues were prepared in the three separate matrixes and the calibration curves generated are tabulated in Table 1. The gas wash bottles were then connected with a 6 inch tube in tandem to a vacuum pump intermediated by a gas flow regulator. The lack of quality control results in patients potentially being exposed to cannabis contaminated with toxic levels of pesticides. As more states legislate and regulate cannabis products, a strong regulatory approach will help to reduce the potential public health and safety consequences from pesticide exposure. Although not yet directly quantified, additional health complications in patients may become a contingency of pesticide exposure and may also interfere with long-term cannabis use studies.

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Description: Consequently, tobacco is only monitored for compliance with US EPA approved pesticides while the residue levels are not federally regulated [ 2 ]. All matrixes and plant material samples were ensured to be free of the pesticides of interest before use and further analysis. This site does not store any files on its server. Subscribe to Table of Contents Alerts. View at Google Scholar R. While these limits represent residues on plant material at levels lower than the levels utilized in this study, a number of samples seen have failed considerably further supporting previous findings by local authorities [ 4 ]. Recoveries of residues were as high as In addition, the awareness of proper and safe pesticide use and application is very important to any crop that will be consumed, especially one that will be inhaled. After having twelve different current medical cannabis patients inhale through the end of a tube attached to the valve while instructed to emulate the draw strength they typically use for these smoking devices, it was determined that the draw rate of an average smoking device user was approximately 1. As mentioned previously, the effects of filtration have a significant impact on the total residues consumed.
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